Respiratory sensitizer means a chemical that will lead to hypersensitivity of the airways following inhalation of the chemical (See Appendix A to 29 CFR 1910.1200, section A.4.). In contrast to respiratory irritation, respiratory sensitization is an immunological response to previous exposure to a chemical.
Sensitizer or sensitiser may refer to: . Chemical sensitizer, a chemical that causes allergic reaction in normal tissue after exposure; Explosive sensitizer, a chemical that promotes the rate of propagation of an explosive; see Chemical explosive#Sensitizer
An early link between cancer and a chemical was found in the late 1700s. In crystallography, atomic packing factor (APF), packing efficiency, or packing fraction is the fraction of volume in a crystal structure that is occupied by constituent particles. It is a dimensionless quantity and always less than unity. In atomic systems, by convention, the APF is determined by assuming that atoms are rigid spheres. The radius of the spheres is taken to be the maximum value 2019-12-12 It establishes the set of criteria to which a drug substance or drug product should conform to be considered acceptable for its intended use.
Information and translations of sensitizer in the most comprehensive dictionary definitions resource on the web. A respiratory sensitiser is a substance which when inhaled can trigger an irreversible allergic reaction in the respiratory system. Once this sensitisation reaction has taken place, further exposure to the substance, even to the tiniest trace, may produce symptoms. 27th March, 2019. The 9 COSHH Hazard Symbols (Meanings And What They Look Like) If you are working with chemicals that are hazardous to health, or completing COSHH risk assessments, you should be aware of the symbols that are included on the packaging of substances, and what they mean. Respiratory sensitising (Sr) – Recognised respiratory sensitiser: comes from a harmonised C&L classifying the substance as Resp.
Hazard sensitiser. A chemical that can cause an allergic reaction in the airways following CLP – What could this mean?
GHS classifies a substance as a skin sensitizer if: (a) “there is evidence in humans that the substance can lead to sensitization by skin contact in a substantial number of persons,” or (b) “there are positive results from an appropriate animal test” .
Repeated exposure to the sensitiser, impaired skin barrier like in Given the special risks that substances classifiedas carcinogenic, mutagenic or toxic for packaging andlabelling of dangerous substances (2), may entail for human or toxic for reproduction categories 1, 2 or 3, or as a respiratory sensitiser. including such use by reproduction in copies or audio or by any other means, Given the special risks that substances classifiedas carcinogenic, mutagenic or toxic packaging andlabelling of dangerous substances (2), may entail for human within the meaning of Directive 2006/115/EC of the European Parliament and of or toxic for reproduction categories 1, 2 or 3, or as a respiratory sensitiser. Can a company wishing to provide information for substances and mixtures for which an SDS is not required, use the SDS format?
Animal experience or test data that indicate that the substance/mixture causes reversible damage to the skin following exposure of up to 4 hours, mean value of ≥ 2.3 < 4.0 for erythema/eschar or for oedema, or inflammation that persists to the end of the observation period, in 2 of 3 tested animals.
sensitizer. chemical science, chemistry - the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions.
The CLP Regulation: adopts in the EU the Globally Harmonised System (GHS) on the classification and labelling of chemicals;
The first step in regulatory evaluation of substances involves the identification of their intrinsic hazards, including the potential for skin sensitization. This is, quite properly, entirely different from assessment of the risks to human health, which might arise from incorporation of substances i …
GHS classifies a substance as a skin sensitizer if: (a) “there is evidence in humans that the substance can lead to sensitization by skin contact in a substantial number of persons,” or (b) “there are positive results from an appropriate animal test” . History.
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• SENSITISER (noun). Sense 1. Meaning: (chemistry) a substance other than a catalyst that facilitates the start of a catalytic reaction. 9.
10 cm when transmitted Light dosimetry, tissue oxygenation and sensitiser concentrations.
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b: a substance that sensitizes the skin on first contact so that subsequent contact causes inflammation A sensitizer is defined by OSHA as "a chemical that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the chemical." Definition of sensitizer in the Definitions.net dictionary. Meaning of sensitizer. What does sensitizer mean? Information and translations of sensitizer in the most comprehensive dictionary definitions resource on the web. A respiratory sensitiser is a substance which when inhaled can trigger an irreversible allergic reaction in the respiratory system. Once this sensitisation reaction has taken place, further exposure to the substance, even to the tiniest trace, may produce symptoms. 27th March, 2019.